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DC1SMe

CAS number:501666-85-9    molecular formula:C35H30ClN5O4S2

overview

compound introduction

DC1Sme, a DC1 derivative, exhibits IC 50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin . DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer . Form:Solid IC50& Target:Duocarmycins

Specs

Chinese alias直流1SMe
English alias-
CAS number501666-85-9molecular formulaC35H30ClN5O4S2
molecular weight684.23 g/molExact mass≥98%
PSA181.000 Ųlogp5.800

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