DC1Sme, a DC1 derivative, exhibits IC 50 values of 22 pM, 10 pM, 32 pM and 250 pM for Ramos, Namalwa, HL60/s and COLO 205 cancer cells, respectively. DC1, an analogue of the minor groove-binding DNA alkylator CC-1065, is a ADC Cytotoxin . DC1 can be used in synthesis of antibody-drug conjugates for the targeted treatment of cancer . Form:Solid IC50& Target:Duocarmycins
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DC1SMe
CAS number:501666-85-9 molecular formula:C35H30ClN5O4S2
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| Chinese alias | 直流1SMe | ||
| English alias | - | ||
| CAS number | 501666-85-9 | molecular formula | C35H30ClN5O4S2 |
| molecular weight | 684.23 g/mol | Exact mass | ≥98% |
| PSA | 181.000 Ų | logp | 5.800 |
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