DIBAC-GGFG-NH2CH2-Dxd (compound LP4) 是一种喜树碱衍生物,也是 Camptothecin的衍生物,是蛋白质-活性分子偶联物的连接载体。Dxd (HY-13631D) 可用作抗体偶联药物 ADC (DS-8201a) 的有效载荷。DIBAC-GGFG-NH2CH2-Dxd 是一种点击化学试剂。它包含一个 DBCO 基团,该基团可以与含有叠氮基团的分子发生应变促进的炔-叠氮环加成反应 (SPAAC)。 体外研究: ADC 由一种抗体组成,ADC 细胞毒素通过 ADC 接头连接到该抗体上。 Powder: 4°C 2 years In solvent: -80°C 6 months -20°C 1 month
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DIBAC-GGFG-NH2CH2-Dxd
CAS number:2758875-01-1 molecular formula:C61H58FN9O12
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 2758875-01-1 | molecular formula | C61H58FN9O12 |
| molecular weight | 1128.16 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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