酸官能化的环辛炔衍生物。环辛炔可用于应变促进的无铜叠氮化物-炔烃点击化学反应。该氮杂二苯并环辛炔可与叠氮官能化化合物或生物分子发生反应，而不需要Cu(I) 催化剂以产生稳定的三唑键。 应用 二苯并环辛炔酸可用于八臂聚（乙二醇）的表面改性，使易于与PEG-双叠氮化物应变促进炔-叠氮化物环加合（SPAAC），以导致水凝胶的形成。这些水凝胶可用于蛋白质固定。 Acid functionalized cyclooctyne derivative. Cyclooctynes are useful in strain-promoted copper-free azide-alkyne click chemistry reactions. This azadibenzocyclooctyne will react with azide functionalized compounds or biomolecules without the need for a Cu(I) catalyst to result in a stable triazole linkage.Dibenzocyclooctyne-acid may be used for the surface modification of eight-arm poly(ethylene glycol), to make it susceptible to strain promoted alkyne-azide cycloaddition (SPAAC) with PEG-bis-azide leading to the formation of hydrogels. These hydrogels are useful for protein immobilization.
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Dibenzocyclooctyne-acid
CAS number：1425485-72-8 molecular formula：C21H19NO3
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Specs
| Chinese alias | DBCO酸 | 二苯并环辛炔酸 | ||
| English alias | DBCO-Acid | ||
| CAS number | 1425485-72-8 | molecular formula | C21H19NO3 |
| molecular weight | 333.38 g/mol | Exact mass | ≥95% |
| PSA | 57.600 Ų | logp | 3.000 |
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