Propargyl-PEG5-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.
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Propargyl-PEG5-t-butyl ester
CAS number:1245823-50-0 molecular formula:C18H32O7
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Specs
| Chinese alias | - | ||
| English alias | propargyl-PEG5-t-butyl ester | tert-butyl 3-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]propanoate | Propargyl-PEG5-COOtBu | Alkyne-PEG5-CH2CH2COOtBu | BP-20651 | AMY4515 | AS-80072 | s10499 | tert-Butyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate | | ||
| CAS number | 1245823-50-0 | molecular formula | C18H32O7 |
| molecular weight | 360.5 g/mol | Exact mass | ≥98% |
| PSA | 72.500 Ų | logp | 0.400 |
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