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Propargyl-PEG5-t-butyl ester

CAS number:1245823-50-0    molecular formula:C18H32O7

overview

compound introduction

Propargyl-PEG5-t-butyl ester is a PEG derivative containing a propargyl group and a t-butyl protected carboxyl group. The propargyl group can be reacted with azide-bearing compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage. The t-butyl protected carboxyl group can be deprotected under acidic conditions. The hydrophilic PEG spacer increases solubility in aqueous media.

Specs

Chinese alias-
English aliaspropargyl-PEG5-t-butyl ester | tert-butyl 3-[2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethoxy]propanoate | Propargyl-PEG5-COOtBu | Alkyne-PEG5-CH2CH2COOtBu | BP-20651 | AMY4515 | AS-80072 | s10499 | tert-Butyl 4,7,10,13,16-pentaoxanonadec-18-yn-1-oate |
CAS number1245823-50-0molecular formulaC18H32O7
molecular weight360.5 g/molExact mass≥98%
PSA72.500 Ųlogp0.400

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