Luffariellolide 是人滑膜蛋白磷脂酶A2 (HSF-PLA2) 抑制剂 (IC50=5 μM)。Luffariellolide 有效抑制佛波酯 (PMA) 引起的耳水肿(ED50=50 μg/耳)。 Luffariellolide is an inhibitor of human synovial fluid phospholipase A2 (HSF-PLA2) (IC50=5 μM). Luffariellolide effectively inhibits phorbol ester (PMA)-induced ear edema (ED50=50 μg/ear).
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Luffariellolide
CAS number:111149-87-2 molecular formula:C25H38O3
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Specs
| Chinese alias | 3-[(3E,7E)-4,8-二甲基-10-(2,6,6-三甲基环己烯-1-基)癸-3,7-二烯基]-2-羟基-2H-呋喃-5-酮 | ||
| English alias | BDBM50478547 | SMP2_000178 | AKOS025294086 | CHEBI:181926 | J-002531 | Luffariellolide | 3-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trimethylcyclohexen-1-yl)deca-3,7-dienyl]-2-hydroxy-2H-furan-5-one | NSC622149 | NSC-622149 | 3-[(3E,7E)-4,8-dimethyl-10-(2,6,6-trim | ||
| CAS number | 111149-87-2 | molecular formula | C25H38O3 |
| molecular weight | 386.57 g/mol | Exact mass | ≥98% |
| PSA | 46.500 Ų | logp | 6.000 |
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