CAS number：947669-86-5 molecular formula：C29H26N2O4
WWL113 是 选择性的 Ces3 和 Ces1f 的抑制剂，其对 Ces3 和 Ces1f 的 IC50 值分别为 120 nM 和 100 nM。WWL113 对 60-kDa丝氨酸水解酶(或水解酶)有极好的选择性。 WWL113 is a selective and orally active Ces3 and Ces1f inhibitor, with IC50 values of 120 nM and 100 nM for Ces3 and Ces1f, respectively. WWL113 appears to show excellent selectivity for the 60-kDa serine hydrolase (or hydrolases).
| Chinese alias | 4'-[[[[甲基[[3-(4-吡啶基苯基)甲基]氨基]羰基]氧基]-[1,1'-联苯] -4-羧酸乙酯 | ||
| English alias | WWL113 | 4′-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amino]carbonyl]oxy]-[1,1′-Biphenyl]-4-carboxylic acid ethyl ester | Ethyl 4′-((methyl(3-(pyridin-4-yl)benzyl)carbamoyl)oxy)-[1,1′-biphenyl]-4-carboxylate | 4'-[[[Methyl[[3-(4-pyridinyl)phenyl]methyl]amin | ||
| CAS number | 947669-86-5 | molecular formula | C29H26N2O4 |
| molecular weight | 466.53 g/mol | Exact mass | ≥98% |
| PSA | 68.700 Ų | logp | 5.600 |
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