PF-05175157 是一种广谱乙酰辅酶 A 羧化酶 (ACC) 抑制剂,对 ACC1 (human),ACC2 (human), ACC1 (rat) 和 ACC2 (rat) 的 IC50 值分别为 27.0, 33.0, 23.5 和 50.4 nM Product Application: PF-05175157 is broad spectrum acetyl-CoA carboxylase (ACC) inhibitor with IC50s of 27.0, 33.0, 23.5 and 50.4 nM for ACC1 (human), ACC2 (human), ACC1 (rat), ACC2 (rat), respectively. Product Describtion: PF-05175157 has been used as an acetyl-Coenzyme A carboxylase (ACC) inhibitor to study its effects on the infection of flavivirus.
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PF 05175157
CAS number:1301214-47-0 molecular formula:C23H27N5O2
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Specs
| Chinese alias | 1,4-二氢-1'-[(2-甲基-1H-苯并咪唑-6-羰基)-1,4-二氢螺并[吲唑-5,4'-哌啶]-7(6H)-酮 | 1-异丙基-1-(2-甲基-1H-苯并[d]咪唑-6-羰基)-1,4-二氢螺并[吲唑-5,4-哌啶] -7(6H)-酮 | ||
| English alias | Z2327390391 | NCGC00421916-02 | s6672 | BCC21447 | (3-Methyl-5-isopropylphenyl)-N-methylcarbamat [German] | 1'-(2-methyl-3H-benzimidazole-5-carbonyl)-1-propan-2-ylspiro[4,6-dihydroindazole-5,4'-piperidine]-7-one | 1-Isopropyl-1'-(2-methyl-1H-benzo[d]imida | ||
| CAS number | 1301214-47-0 | molecular formula | C23H27N5O2 |
| molecular weight | 405.49 g/mol | Exact mass | ≥98%(HPLC) |
| PSA | 83.900 Ų | logp | 2.7 |
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