compound introduction
6- [4-（1H-咪唑-1-基）苯氧基] -N，N-二甲基-1-己胺盐酸盐是花生四烯酸在脉管系统中的重要代谢产物，尤其是在肾脏中，是由细胞色素合成的4A家族的P450（CYP450）酶。1,2，烷基芳基咪唑显示抑制某些CYP450酶，包括CYP4A，与20-HETE合成有关。 6-[4-(1H-imidazol-1-yl)phenoxy]-N,N-dimethyl-1-hexanamine, dihydrochloride is an important metabolite of arachidonic acid in the vasculature, especially in the kidney, where it is synthesized by cytochrome P450 (CYP450) enzymes of the 4A family.1,2 Alkylaryl imidazoles show to inhibit certain CYP450 enzymes, including CYP4A, which is associated with 20-HETE synthesis.
