在人肾微粒体中测试时,20-HETE合酶CYP4A11的选择性抑制剂显示IC | 50 |为8.8 nM。作为1A,1C和3A CYP450酶抑制剂的效力较低。 A selective inhibitor of the 20-HETE synthase CYP4A11 displaying an IC|50|value of 8.8 nM when tested in human renal microsomes. Less potent as an inhibitor of 1A, 1C, and 3A CYP450 enzymes.
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CAY10434
CAS number:769917-29-5 molecular formula:C17H25N3O
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| Chinese alias | - | ||
| English alias | 6- [4- (1H- imidazol- 1- yl)phenoxy]- N, N- dimethyl- 1- hexanamine | ||
| CAS number | 769917-29-5 | molecular formula | C17H25N3O |
| molecular weight | 287.4 g/mol | Exact mass | ≥98% |
| PSA | 30.300 Ų | logp | 3.100 |
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