CAS number：883973-99-7 molecular formula：C13H7Cl3N2O3S
FBPase-1抑制剂是一种细胞可渗透的苯并恶唑磺酰胺化合物，可通过在AMP变构结合位点竞争来抑制hFBPase-1的酶活性。FBPase-1抑制剂已显示出可以在饥饿的大鼠肝癌细胞中阻断葡萄糖的产生。 应用 FBPase-1抑制剂，通过在AMP变构结合位点竞争来抑制hFBPase-酶活性。FBPase-1抑制剂已被证明可阻断饥饿大鼠肝癌细胞中葡萄糖的产生。 FBPase-1 Inhibitor is a cell-permeable benzoxazolo-sulfonamide compound that inhibits hFBPase-1 enzymatic activity by competing at the AMP allosteric binding site. FBPase-1 Inhibitor has been shown to block glucose production in starved rat hepatoma cells.
| Chinese alias | 2,5-二氯-N-(5-氯苯并[d]恶唑-2-基)苯磺酰胺 | ||
| English alias | Fructose 1,6-bisphosphatase-1 Inhibitor | ||
| CAS number | 883973-99-7 | molecular formula | C13H7Cl3N2O3S |
| molecular weight | 377.63 g/mol | Exact mass | ≥97% |
| PSA | 80.600 Ų | logp | 4.500 |
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