CAS number：193807-60-2 molecular formula：C21H20N2O4S
MMP-2 / MMP-9抑制剂II是MMP-2（IC | 50 | = 17 nM）和MMP-9（IC | 50 | = 30 nM）的有效抑制剂。MMP-2 / MMP-9抑制剂II已显示出诱导并快速激活HIF的作用。还报道了在鼠模型中抑制路易斯肺癌诱导的肺部定植。 MMP-2/MMP-9 Inhibitor II is a potent inhibitor of MMP-2 (IC|50|= 17 nM) and MMP-9 (IC|50|= 30 nM). MMP-2/MMP-9 Inhibitor II has been shown to induce and rapidly activate HIF. Also reported to inhibit Lewis lung carcinoma-induced lung colonization in a murine model.
| Chinese alias | - | ||
| English alias | (2R)-N-hydroxy-3-phenyl-2-[(4-phenylphenyl)sulfonylamino]propanamide | ||
| CAS number | 193807-60-2 | molecular formula | C21H20N2O4S |
| molecular weight | 396.46 g/mol | Exact mass | ≥95% |
| PSA | 104.000 Ų | logp | 3.400 |
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