二十碳三烯酸（5Z，11Z，14Z）是一种多不饱和脂肪酸，存在于各种天然资源中，包括海生松（Pinus pinaster）种子油（MPSO），裸子植物的叶子和种子以及淡水腹足动物。在表达人ApoA1的转基因小鼠中，含MPSO的饮食降低了高密度脂蛋白和ApoA1的水平。发现MPSO可以降低体外胆固醇流出。当局部使用5Z，11Z，14Z-二十碳三烯酸甲酯时，可能会通过从磷脂库中置换花生四烯酸并减少下游的炎症产物（例如前列腺素E2和白三烯）来减少炎症过程。 Eicosatrienoic Acid (5Z,11Z,14Z) is a polyunsaturated fatty acid found in various natural sources including maritime pine (Pinus pinaster) seed oil (MPSO), gymnospermae leaves and seeds, and freshwater gastropods. A diet containing MPSO lowered high-density lipoprotein and ApoA1 levels in transgenic mice expressing human ApoA1. MPSO was found to diminish cholesterol efflux in vitro. 5Z,11Z,14Z-Eicosatrienoic acid methyl ester, when topically applied, diminishes inflammatory processes, potentially by displacing arachidonic acid from phospholipid pools and reducing downstream inflammatory products such as prostaglandin E2 and leukotrienes.
All
Chemical Reagents
Biomedicine
Organic raw materials
Inorganic chemical industry
intermediate
Agricultural chemicals
Auxiliaries and catalysts
Fragrances and Flavors
Dyes and Pigments
Daily chemical industry
Eicosatrienoic Acid (5Z,11Z,14Z)
CAS number：7019-85-4 molecular formula：C20H34O2
overview
compound introduction
Specs
| Chinese alias | - | ||
| English alias | (Z,Z,Z)-5,11,14-Eicosatrienoic acid | SR-01000946329 | .DELTA.5,11,14-EICOSATRIENOIC ACID | 5,11,14-Eicosatrienoic acid | Trimethoxy 4-2'-4' chalcone [French] | DTXSID601317197 | E-365 | all-cis-5,11,14-eicosatrienoic acid | (5Z,11Z,14Z)-icosatrienoic aci | ||
| CAS number | 7019-85-4 | molecular formula | C20H34O2 |
| molecular weight | 306.48 g/mol | Exact mass | ≥98% |
| PSA | 37.300 Ų | logp | 6.700 |
numbering system
No numbering system information yet
physicochemical properties
No physical and chemical property information yet
Safety information
No safety information yet
Production methods and uses
No production method and use information yet
Related
upstream information
No upstream information yet
downstream information
No downstream information yet
MSDS
Found 0 shareMSDS
