Estrone 3-O-Sulfamate是一种有效的ES(雌酮硫酸酯酶)抑制剂。在完整的MCF-7细胞中,Estrone 3-O-Sulfamate在0.1μM时抑制雌酮硫酸酯酶> 99%,IC | 50 | = 65pM。 Estrone 3-O-Sulfamate is a potent inhibitor of ES (estrone sulfatase). Estrone 3-O-Sulfamate inhibits estrone sulfatase >99% at 0.1μM in intact MCF-7 cells, IC|50|=65pM.
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Estrone 3-O-Sulfamate
CAS number:148672-09-7 molecular formula:C18H23NO4S
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Specs
| Chinese alias | [(8R,9S,13S,14S)-13-甲基-17-氧代-7,8,9,11,12,14,15,16-八氢-6H-环戊二烯并[a]菲-3-基]氨基磺酸 | ||
| English alias | BDBM50134329 | 1,8-dihydroxy-anthraquinone | 17-Oxoestra-1,3,5(10)-triene-3-yl Sulfamate | DAC 893 | Estrone-3-O-sulfamate | estrone3-O-sulfamate | Estrone 3-O-Sulfamate | RVKFQAJIXCZXQY-CBZIJGRNSA-N | SCHEMBL305660 | Sulfamic acid (8R,9S,13S,14S)-13-meth | ||
| CAS number | 148672-09-7 | molecular formula | C18H23NO4S |
| molecular weight | 349.44 g/mol | Exact mass | ≥97% |
| PSA | 94.800 Ų | logp | 2.400 |
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