11-脱氢-TXB2 是一种长期存在的重要代谢产物，是TXA2的水合后产生的血栓素B2进入血液后的产物。它是用于测量体内血栓烷产量的可靠参数。它也是检测血小板活化综合征可能引起的人体内TXA2阶段性释放的合适分析工具。可以使用放射免疫分析法进行检测。 11-Dehydro-TXB2 is a long-lived prominent metabolite and product of infused thromboxane B2 (TXB2), the hydration product of biologically active TXA2, in the urine and blood of several species. It is a reliable parameter for measuring thromboxane production in vivo. It is also an appropriate analytical tool for the detection of the phasic release of TXA2 in human circulation that might occur from platelet activation syndromes. It can be detected using radioimmunoassay. 11-dehydro TXB, is supplied as a solution in methyl acetate. To change the solvent, simply evaporate the methyI acetate under a gentle stream of nitrogen and immediately add the solvent of choice. Solvents such as ethanol, DMSO, and dimethyl formamide purged with an inert gas can be used. The solubility of 11-dehydro TXB, in these solvents is approximately 100, 25, 50 mg/ml, respectively.
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11-Dehydro-TXB2
CAS number：67910-12-7 molecular formula：C20H32O6
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compound introduction
Specs
| Chinese alias | - | ||
| English alias | 11-keto TXB2 | 11-dehydro TXB2 | 11-dehydro Thromboxane B2 | ||
| CAS number | 67910-12-7 | molecular formula | C20H32O6 |
| molecular weight | 368.47 g/mol | Exact mass | - |
| PSA | 104.000 Ų | logp | 2.600 |
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