YUM70 是一种有效的 glucose-regulated protein 78 (GRP78) 抑制剂,IC50 为 1.5 μM。YUM70 在胰腺癌中诱导内质网 (endoplasmic reticulum, ER) 应激介导的细胞凋亡。 Information YUM70 is a potent inhibitor ofglucose-regulated protein 78 (GRP78)inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.
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YUM70
CAS number:423145-35-1 molecular formula:C21H19ClN2O4
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| Chinese alias | - | ||
| English alias | Butanamide,N-[1,3-benzodioxol-5-yl(5-chloro-8-hydroxy-7-quinolinyl)methyl]- | ||
| CAS number | 423145-35-1 | molecular formula | C21H19ClN2O4 |
| molecular weight | 398.84 g/mol | Exact mass | 10mM in DMSO |
| PSA | 80.700 Ų | logp | 4.500 |
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