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YUM70

CAS number:423145-35-1    molecular formula:C21H19ClN2O4

overview

compound introduction

YUM70 是一种有效的 glucose-regulated protein 78 (GRP78) 抑制剂,IC50 为 1.5 μM。YUM70 在胰腺癌中诱导内质网 (endoplasmic reticulum, ER) 应激介导的细胞凋亡。 Information YUM70 is a potent inhibitor ofglucose-regulated protein 78 (GRP78)inhibitor with an IC50 of 1.5 μM. YUM70 induces endoplasmic reticulum (ER) stress-mediated apoptosis in pancreatic cancer.

Specs

Chinese alias-
English aliasButanamide,N-​[1,​3-​benzodioxol-​5-​yl(5-​chloro-​8-​hydroxy-​7-​quinolinyl)​methyl]​-
CAS number423145-35-1molecular formulaC21H19ClN2O4
molecular weight398.84 g/molExact mass10mM in DMSO
PSA80.700 Ųlogp4.500

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