CAS number：1358099-18-9 molecular formula：C26H31N7O
Information C25-140 C25-140 is a small-molecule inhibitor of TRAF6-Ubc13 interaction . C25-140 directly binds to TRAF6, thereby blocking the interaction of TRAF6 with Ubc13, and as a consequence lowers TRAF6 activity. C25-140 impedes NF-κB activation in various immune and inflammatory signaling pathways also in primary human and murine cells. Targets TRAF6-Ubc13 ; NF-κB
| Chinese alias | 1-(4-Benzylpiperidin-1-yl)-3-(3,5-dimethyl-1-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl)propan-1-one | ||
| English alias | 1-Propanone,3-[3,5-dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]- | ||
| CAS number | 1358099-18-9 | molecular formula | C26H31N7O |
| molecular weight | 457.57 g/mol | Exact mass | ≥98% |
| PSA | 81.200 Ų | logp | 3.600 |
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