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E6446 dihydrochloride

CAS number:1345675-25-3    molecular formula:C27H37Cl2N3O3

overview

compound introduction

Information E6446 dihydrochloride E6446 dihydrochloride is a specific Toll-like receptor 9 inhibitor. Targets TLR9 In vivo E6446 is orally bioavailable (20%) and has high volumes of distribution in mice (95.9 l/kg).

Specs

Chinese aliasE6446 二盐酸盐
English aliasBenzoxazole,6-​[3-​(1-​pyrrolidinyl)​propoxy]​-​2-​[4-​[3-​(1-​pyrrolidinyl)​propoxy]​phenyl]​-​,hydrochloride (1:2)
CAS number1345675-25-3molecular formulaC27H37Cl2N3O3
molecular weight522.51 g/molExact mass≥98%
PSA51.000 Ųlogp5.336

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