Information E6446 dihydrochloride E6446 dihydrochloride is a specific Toll-like receptor 9 inhibitor. Targets TLR9 In vivo E6446 is orally bioavailable (20%) and has high volumes of distribution in mice (95.9 l/kg).
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E6446 dihydrochloride
CAS number:1345675-25-3 molecular formula:C27H37Cl2N3O3
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| Chinese alias | E6446 二盐酸盐 | ||
| English alias | Benzoxazole,6-[3-(1-pyrrolidinyl)propoxy]-2-[4-[3-(1-pyrrolidinyl)propoxy]phenyl]-,hydrochloride (1:2) | ||
| CAS number | 1345675-25-3 | molecular formula | C27H37Cl2N3O3 |
| molecular weight | 522.51 g/mol | Exact mass | ≥98% |
| PSA | 51.000 Ų | logp | 5.336 |
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