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JZL184

CAS number:1101854-58-3    molecular formula:C27H24N2O9

overview

compound introduction

JZL 184 是一种有效的,选择性的且不可逆的 MAGL 抑制剂,可阻断脑膜中的 2-花生四烯酸甘油酯 (2-AG) 的水解 (IC50 为 8 nM)。JZL 184 对 MAGL 的选择性比 FAAH 高 300 倍以上。 application: JZL 184 has been used as an inhibitor of monoacylglycerol lipase to study its effect on human osteoblast differentiation and proliferation and postsynaptic neurons.

Specs

Chinese alias-
English alias4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl-(hydroxy)methyl)piperidine-1-carboxylate | AKOS024457824 | HY-15249 | Q27893460 | BRD-K45446451-001-01-9 | NCGC00263237-07 | HMS3652L12 | NSC763094 | NSC-763094 | US9133148, A | SCHEMBL15094611 | 4-[Bis(1,3-benz
CAS number1101854-58-3molecular formulaC27H24N2O9
molecular weight520.5 g/molExact mass-
PSA133.000 Ųlogp4.200

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