RO8994是一种高效的选择性MDM2抑制剂, IC50为nM (HTRF结合检测) 和20 nM (MTT增殖检测),在 HTRF 结合试验中的 IC50 值为 5 nM,在 MTT 增殖试验中的 IC50 值为 20 nM。
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RO8994
CAS number:1309684-94-3 molecular formula:C31H31Cl2FN4O4
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Specs
| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1309684-94-3 | molecular formula | C31H31Cl2FN4O4 |
| molecular weight | 613.51 g/mol | Exact mass | ≥98% |
| PSA | 123.000 Ų | logp | 5.000 |
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