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T0901317

CAS number:293754-55-9    molecular formula:C17H12F9NO3S

overview

compound introduction

T0901317是一个强的和选择性的LXR和FXR激动剂,EC50分别是50 nM和5 μM,能够抑制核里的NF/κB。A cell-permeable, nonsterol compound that acts as a highly potent LXR activator T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. A cell-permeable, nonsterol compound that acts as a highly potent LXR activator

Specs

Chinese alias-
English aliasT-0901317 | T 0901317 | N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide
CAS number293754-55-9molecular formulaC17H12F9NO3S
molecular weight481.33 g/molExact mass-
PSA66.000 Ųlogp4.900

numbering system

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physicochemical properties

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Production methods and uses

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