T0901317是一个强的和选择性的LXR和FXR激动剂,EC50分别是50 nM和5 μM,能够抑制核里的NF/κB。A cell-permeable, nonsterol compound that acts as a highly potent LXR activator T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 μM, respectively. A cell-permeable, nonsterol compound that acts as a highly potent LXR activator
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T0901317
CAS number:293754-55-9 molecular formula:C17H12F9NO3S
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Specs
| Chinese alias | - | ||
| English alias | T-0901317 | T 0901317 | N-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2,2,2-trifluoroethyl)benzenesulfonamide | ||
| CAS number | 293754-55-9 | molecular formula | C17H12F9NO3S |
| molecular weight | 481.33 g/mol | Exact mass | - |
| PSA | 66.000 Ų | logp | 4.900 |
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