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RO5461111

CAS number:1252637-46-9    molecular formula:C27H24F6N4O4S

overview

compound introduction

RO5461111 a highly specific and orally active antagonist of Cathepsin S with IC 50 s of 0.4 nM (human Cathepsin S ) and 0.5 nM (murine Cathepsin S ), respectively. RO5461111 can effectively inhibit the activation of antigen-specific T cells and B cells. RO5461111 can improve pulmonary inflammation and lupus nephritis

Specs

Chinese alias-
English alias-
CAS number1252637-46-9molecular formulaC27H24F6N4O4S
molecular weight614.56 g/molExact mass≥98%
PSA-logp-

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