Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer. Appearance:Solid In Vitro:Paclitaxel is conjugated to a brain peptide vector, Angiopep-2, to provide a paclitaxel– Angiopep-2 conjugate named ANG1005. ANG1005 enters the brain to a greater extent than paclitaxel and bypasses the P-gp. ANG1005 has an antineoplastic potency similar In Vivo:ANG1005 administration leads to a significant increase in the survival of mice with intracerebral implantation of U87 MG glioblastoma cells or NCI-H460 lung carcinoma cells. MCE has not independently confirmed the accuracy of these methods. They are Biological Activity:Angiopep-2 hydrochloride is a brain peptide vector. The conjugation of anticancer agents with the Angiopep-2 peptide vector could increase their efficacy in the treatment of brain cancer.
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Angiopep-2 hydrochloride
CAS number：unknown molecular formula：C104H150ClN29O31
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| Chinese alias | 血管肽-2盐酸盐 | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | C104H150ClN29O31 |
| molecular weight | 2337.93 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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