Information Pteryxin Pteryxin ((+)-Pteryxin), a dihydropyranocoumarin derivative found in Apiaceae family, is a potent inhibitor of butyrylcholinesterase (BChE) with IC50 of 12.96 μg/ml. Pteryxin inhibits LPS-induced nitric oxide production in mouse peritoneal macrophages with IC50 of 20 µM. Pteryxin is potential for Alzheimer's disease (AD) treatment. Targets BChE (Cell-free assay); nitric oxide (in mouse peritoneal macrophages) 12.96 μM; 20 μM
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Pteryxin
CAS number:13161-75-6 molecular formula:C21H22O7
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| Chinese alias | - | ||
| English alias | (+)-(3'R,4'R)-3'-ACETYL-4'-ANGELOYLKHELLACTONE | 2-Butenoic acid, 2-methyl-, 9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo(1,2-b:3,4-b')dipyran-10-yl ester, (9R-(9alpha,10alpha(Z)))- | UNII-C1G8A9744Z | AKOS015969719 | AC1NQYG8 | [(9R,10R)-9-a | ||
| CAS number | 13161-75-6 | molecular formula | C21H22O7 |
| molecular weight | 386.4 g/mol | Exact mass | 10mM in DMSO |
| PSA | 88.100 Ų | logp | 3.502 |
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