CAS number：946387-07-1 molecular formula：C14H22C12N2O2S
在室温下运输。 RN-1734 是一种选择性 TRPV4 通道拮抗剂，完全拮抗 4αPDD 介导的 TRPV4 活化，作用于 hTRPV4, mTRPV4, 和 rTRPV4，IC50 分别为 2.3 μM、5.9 μM、3.2 μM。RN-1734 能明显降低肿瘤坏死因子 α (TNF-α) 和白细胞介素 1β (IL-1β) 的产生，而不改变 olig2- 阳性细胞的数量。 Shipped at Room Temperature. Application RN-1734 has been used as a transient receptor potential vanilloid 4 (TRPV4) blocker to study its effects on differentiation of a corneal epithelial cell model, RCE1(5T5) cells.
| Chinese alias | 2,4-二氯-N-丙-2-基-N-[2-(丙-2-基氨基)乙基]苯磺酰胺 | ||
| English alias | HY-19975 | AKOS005110777 | BDBM50426575 | SCHEMBL20304906 | RN-1734, >=98% (HPLC) | TRPV4 Antagonist I, RN-1734 | BCP28123 | TRPV4 Antagonist I, RN-1734 - CAS 946387-07-1 | 2,4-Dichloro-N-isopropyl-N-(2-isopropylaminoethyl)benzenesulfonamide | HMS3414D05 | ||
| CAS number | 946387-07-1 | molecular formula | C14H22C12N2O2S |
| molecular weight | 353.31 g/mol | Exact mass | - |
| PSA | 57.800 Ų | logp | 3.500 |
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