LY2456302是一种有效地可渗透中枢神经的kappa opioid受体拮抗剂,Ki值为0.807 nM。 LY2456302 is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).
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LY2456302
CAS number:1174130-61-0 molecular formula:C26H27FN2O2
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Specs
| Chinese alias | (S)-4-(4-((2-(3,5-二甲基苯基)吡咯烷-1-基)甲基)苯氧基)-3-氟苯甲酰胺 | ||
| English alias | Aticaprant | LY-2456302 | CERC-501 | (S)-4-(4-((2-(3,5-Dimethylphenyl)pyrrolidin-1-yl)methyl)phenoxy)-3-fluorobenzamide | ||
| CAS number | 1174130-61-0 | molecular formula | C26H27FN2O2 |
| molecular weight | 418.50 g/mol | Exact mass | - |
| PSA | 55.600 Ų | logp | 5 |
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