JNJ-18038683 是 5-羟色胺受体 7 (5-HT7) 的拮抗剂,HEK293 细胞中检测出其对大鼠和人类 5-羟色胺受体 7 的 pKi 值分别为 8.19,8.20。 JNJ-18038683 is a 5-Hydroxytryptamine Type 7 (5-HT7) receptor antagonist, with pKis of 8.19, 8.20 for rat and human 5-HT7 in HEK293 cells, respectively.
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JNJ-18038683
CAS number:851376-05-1 molecular formula:C26H28ClN3O7
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| Chinese alias | - | ||
| English alias | 3-(4-chlorophenyl)-1-(phenylmethyl)-5,6,7,8-tetrahydro-4H-pyrazolo[5,4-d]azepine | 28PGH5X4OQ | SCHEMBL2076477 | GTPL8432 | UNII-28PGH5X4OQ | 3-(4-Chlorophenyl)-1,4,5,6,7,8-hexahydro-1-(phenylmethyl)pyrazolo[3,4-d]azepine | JNJ-18038683 free base | ||
| CAS number | 851376-05-1 | molecular formula | C26H28ClN3O7 |
| molecular weight | 529.97 g/mol | Exact mass | - |
| PSA | 29.900 Ų | logp | 4.000 |
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