TAK-071是一种新型, 高效,选择性的毒蕈碱乙酰胆碱受体1 (M1R)正变构调节剂。 TAK-071激活M1R的EC50为520nM。 TAK-071 is a novel, potent and highly selective muscarinic acetylcholine receptor 1 (M1R) positive allosteric modulator. EC50 of TAK-071 M1R agonist activities is 520 nM.
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TAK-071
CAS number:1820812-16-5 molecular formula:C24H24FN3O3
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| Chinese alias | - | ||
| English alias | D77973 | MS-27399 | TAK-071 | GTPL12302 | 6-(4-(1H-PYRAZOL-1-YL)BENZYL)-4-FLUORO-2-((3S,4S)-4-HYDROXYTETRAHYDRO-2H-PYRAN-3-YL)-5-METHYLISOINDOLIN-1-ONE | AC-31580 | WFSARWQASFQZMG-VXKWHMMOSA-N | ||
| CAS number | 1820812-16-5 | molecular formula | C24H24FN3O3 |
| molecular weight | 421.46 g/mol | Exact mass | - |
| PSA | 67.600 Ų | logp | 2.7 |
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