PF-04745637 is a potent and selective TRPA1 antagonist with an IC 50 of 17 nM for human TRPA1 In Vivo Topically applied PF-04745637 (Compound 8; 50 mg/mL and 100 mg/mL) significantly reduces cinnamaldehyde-mediated flare in rat skin . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:TRPA1 17 nM (IC 50 )
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PF-04745637
CAS number:1917294-46-2 molecular formula:C27H32ClF3N2O2
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 1917294-46-2 | molecular formula | C27H32ClF3N2O2 |
| molecular weight | 509.00 g/mol | Exact mass | ≥98% |
| PSA | 52.600 Ų | logp | 6.100 |
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