CAS number：1310012-12-4 molecular formula：C18H15FN2O
VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC 50 value of 16 nM and a K i of 195 nM, respectively. VU0360172 stimulates polyphosphoinositide (PI) hydrolysis in vivo , which is abrogated in mGlu5 receptors gene deleted mice Form:Solid IC50& Target:EC 50 : 16 nM (mGlu5 receptor), K i : 195 nM (mGlu5 receptor)
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| CAS number | 1310012-12-4 | molecular formula | C18H15FN2O |
| molecular weight | 294.32 g/mol | Exact mass | ≥98% |
| PSA | - | logp | - |
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