CAS number：1008402-47-8 molecular formula：C22H30N4O9
Bis-Mal-PEG3 是一种 PROTAC linker，属于 PEG 类。可用于合成 PROTAC 分子。 Bis-Mal-PEG3 is a PEG derivative containing a two maleimide groups. The maleimide groups will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol. The hydrophilic PEG spacer increases solubility in aqueous media.
| Chinese alias | N,N'-(((氧基双(乙烷-2,1-二基))双(氧基))双(乙烷-2,1-二基))双(3-(2,5-二氧代-2,5-二氢-1H-吡咯-1-基)丙酰胺) | 三乙二醇双琥珀酰亚胺 | ||
| English alias | N,N'-(((Oxybis(ethane-2,1-diyl))bis(oxy))bis(ethane-2,1-diyl))bis(3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamide) | Mal-PEG3-Mal | Mal-NH-PEG3-NH-Mal | ||
| CAS number | 1008402-47-8 | molecular formula | C22H30N4O9 |
| molecular weight | 494.50 g/mol | Exact mass | ≥98% |
| PSA | 161.000 Ų | logp | -3.200 |
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