CAS number：2055015-40-0 molecular formula：C22H42O12S2
Acid-PEG4-SS-PEG4-acid is a cleavable PEG linker with carboxylic acid groups at both terminus. The disulfide bonds can be cleaved via a reduction reaction using Dithiothreitol (DTT) reagent. The terminal carboxylic acids can be reacted with primary amines in the presences of activators such as EDC and DCC to form stable amide bonds. The hydrophilic PEG linkers can increase the water solubility of the compound in aqueous media.
| Chinese alias | 酸-四聚乙二醇-二硫键-四聚乙二醇-酸 | 4,7,10,13,20,23,26,29-八氧杂-16,17-二硫杂三十二烷二酸 | ||
| English alias | 4,7,10,13,20,23,26,29-Octaoxa-16,17-dithiadotriacontanedioic acid | ||
| CAS number | 2055015-40-0 | molecular formula | C22H42O12S2 |
| molecular weight | 562.69 g/mol | Exact mass | ≥95% |
| PSA | 199.000 Ų | logp | -1.300 |
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