Information Triptophenolide Triptophenolide (Hypolide), derived from Tripterygium wilfordii, is a pan-antagonist for wild-type and mutant androgen receptors with the IC50 values of 260 nM for AR-WT, 480 nM for AR-F876L, 388 nM for AR-T877A, and 437 nM for W741C+T877A. Targets AR-WT ; AR-T877A ; AR-F876L 260 nM; 388 nM; 480 nM
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Triptophenolide
CAS number:74285-86-2 molecular formula:C20H24O3
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| Chinese alias | - | ||
| English alias | s9045 | (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e][2]benzofuran-1-one | (3bR,9bS)-6-hydroxy-9b-methyl-7-propan-2-yl-3,3b,4,5,10,11-hexahydronaphtho[2,1-e]isobenzofuran-1-one | CCG-38739 | KBio2_002202 | KBio2_007338 | ||
| CAS number | 74285-86-2 | molecular formula | C20H24O3 |
| molecular weight | 312.4 g/mol | Exact mass | ≥98% |
| PSA | 46.500 Ų | logp | 4.63 |
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74285-86-2 | Triptophenolide.pdf





