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AMD 3465 hexahydrobromide

CAS number:185991-07-5    molecular formula:C24H38N5 · 6HBr

overview

compound introduction

储存在-20℃。存放在干燥的条件下。该产品最多可存储12个月。 AMD 3465 hexahydrobromide (GENZ-644494 hexahydrobromide) 是一种有效的 CXCR4 拮抗剂,在 SupT1 细胞中,能够抑制 12G5 mAb,CXCL12AF647 与 CXCR4 的结合,IC50 值分别为 0.75 nM 和 18 nM;AMD 3465 同时可有效抑制 X4 HIV 的复制 (IC50,1-10 nM),但对 R5 HIV 病毒无作用。 Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Specs

Chinese aliasN-[[4-(1,4,8,11-四氮杂环十四烷基-1-基甲基)苯基]甲基]-2-吡啶甲胺六氢溴化物
English alias-
CAS number185991-07-5molecular formulaC24H38N5 · 6HBr
molecular weight896.07 g/molExact mass10mM in Water
PSA64.300 Ųlogp-

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