Cletoquine (Desethylhydroxychloroquine) 是 Hydroxychloroquine 的主要活性代谢产物,是由 CYP2D6,CYP3A4,CYP3A5 和 CYP2C8 同工酶在肝脏中形成的。Cletoquine 也是一种 Chloroquine 衍生物,具有抗基孔肯雅热病毒 (CHIKV) 的能力。Cletoquine 具有抗疟作用,并可用于自身免疫性疾病的研究。
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Cletoquine
CAS number:4298-15-1 molecular formula:C16H22ClN3O
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| Chinese alias | 氯托喹 | ||
| English alias | Desethylhydroxychloroquine | Cletochina pound>>Desethyl Hydroxy Chloroquine | HY-135810 | GNF-Pf-1952 | 2-[4-[(7-chloroquinolin-4-yl)amino]pentylamino]ethanol | Etazole | 2-(4-(7-chloroquinolin-4-ylamino)pentylamino)ethanol | DESETHYL HYDROXY CHLOROQUINE | ||
| CAS number | 4298-15-1 | molecular formula | C16H22ClN3O |
| molecular weight | 307.82 g/mol | Exact mass | ≥98% |
| PSA | 57.200 Ų | logp | 2.700 |
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