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Kasugamycin Hydrochloride Monohydrate

CAS number:200132-83-8    molecular formula:C14H28ClN3O10

overview

compound introduction

盐酸卡舒霉素是一种氨基糖苷类抗生素,可有效抑制革兰氏阳性和革兰氏阴性细菌并阻止翻译起始。盐酸卡舒霉素在较小程度上还抑制植物致病微生物。研究表明,盐酸卡舒霉素可以与30s核糖体亚基结合,从而间接抑制P位点tRNA结合,并阻止蛋白质合成。 Kasugamycin is an aminoglycoside antibiotic that potently inhibits both gram-positive and gram-negative bacteria and blocks translation initiation. To a weaker extent, Kasugamycin also inhibits phytopathogenic microbes. Research shows that Kasugamycin can associate with the 30s ribosomal subunit, which results in the indirect inhibition of the P-site tRNA binding, and blocks protein synthesis.

Specs

Chinese alias-
English aliasKasugamycin (hydrochloride hydrate) | D-Chiro-inositol, 3-O-(2-amino-4-((carboxyiminomethyl)amino)-2,3,4,6-tetradeoxy-alpha-d-arabino-hexopyranosyl)-, hydrochloride, hydrate (1:1:1) | AKOS030526701 | S5968 | DTXSID20859996 | UNII-5A9BN7V7QL | 3-O-[2-amino
CAS number200132-83-8molecular formulaC14H28ClN3O10
molecular weight433.84 g/molExact mass10mM in Water
PSA222.000 Ųlogp-

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