compound introduction
MK-5172是HCV NS3/4a蛋白酶抑制剂，对1b和1a亚型的IC50分别为7.4 nM和7 nM。 MK-5172 is a novel P2-P4 quinoxaline macrocyclic HCV NS3/4a protease inhibitor currently in clinical development.
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MK-5172
CAS number：1350514-68-9 molecular formula：C38H50N6O9S
overview
Specs
| Chinese alias | - | ||
| English alias | AC-29227 | EN300-19880554 | UNII-8YE81R1X1J | (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-di | Z2608566420 | GRAZOPREVIR [WHO-DD] | Grazoprevir anhydrous | ino[11,12-b]quinoxaline-8- | ||
| CAS number | 1350514-68-9 | molecular formula | C38H50N6O9S |
| molecular weight | 766.9 g/mol | Exact mass | - |
| PSA | 204.000 Ų | logp | 4.7 |
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