DDD85646 是一种有效的布氏锥虫 N-肉豆蔻酰转移酶 (NMT)抑制剂 (TbNMT IC50=2 nm;hNMTIC50 =4 纳米)。N-肉豆蔻酰转移酶 (NMT) 是人类非洲锥虫病的潜在活性分子靶点。
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DDD85646
CAS number:1215010-55-1 molecular formula:C21H24Cl2N6O2S
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compound introduction
Specs
| Chinese alias | compound 1a | IMP-366 | ||
| English alias | 2,6-dichloro-4-[2-(1-piperazinyl)-4-pyridinyl]-N-(1,3,5-trimethyl-1H-pyrazol-4-yl)-benzenesulfonamide | IMP-366 | ||
| CAS number | 1215010-55-1 | molecular formula | C21H24Cl2N6O2S |
| molecular weight | 495.43 g/mol | Exact mass | - |
| PSA | 101.000 Ų | logp | 3.200 |
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