Enfumafungin, a triterpene glycoside, is isolated from extracts derived from fungus Hormonema carpetanum. Enfumafungin is an antifungal compound that is acting on the fungal cell wall, as the (1,3)-beta-D-glucan synthase inhibitor. Enfumafungin is specific for yeasts and fungi (excluding Cryptococcus ) and does not inhibit the growth of Bacillus subtilis In Vitro Enfumafungin (24-48 h) has MICs of less than 0.5 μg/mL against the Candida and Aspergillus species tested and it is inactive against Cryptococcus , including the decapsulated form (MY2062). MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo Enfumafungin (50-200 mg/kg; i.p. twice daily for 2 days) produces a significant decrease in the number of c.f.u. in kidneys of mice challenged with C. albicans , with an ED 90 of 90 mg/kg . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:(1,3)-beta-D-glucan synthase
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Enfumafungin
CAS number：260979-95-1 molecular formula：C38H60O12
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| Chinese alias | 恩夫马芬净 | ||
| English alias | - | ||
| CAS number | 260979-95-1 | molecular formula | C38H60O12 |
| molecular weight | 708.88 g/mol | Exact mass | ≥99% |
| PSA | - | logp | - |
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