CAS number：1062368-24-4 molecular formula：C25H22N6
LDN-193189是一种选择性的BMP信号通路抑制剂，抑制BMP I型受体ALK2和ALK3的转录活性，IC50分别为5 nM和30 nM，作用于BMP比作用于TGF-β选择性高200倍。 LDN193189 is a selective BMP signaling inhibitor, inhibits the transcriptional activity of the BMP type I receptors ALK2 and ALK3 with IC50 of 5 nM and 30 nM, respectively, exhibits 200-fold selectivity for BMP versus TGF-β.
| Chinese alias | - | ||
| English alias | Q27163247 | BCP9000845 | AC-31395 | AS-73735 | DM 3189 hydrochloride | BROMOACETIC-13C2ACID | EX-A424 | BRD-K04853698-003-01-4 | tri-sodium citrate | EX-8677 | NCGC00249389-21 | LDN 193189 | 1062368-24-4 | CHEBI:91387 | LDN193189 free base | 4-{6-[4-(1-pi | ||
| CAS number | 1062368-24-4 | molecular formula | C25H22N6 |
| molecular weight | 479.4 g/mol | Exact mass | ≥98% |
| PSA | 58.400 Ų | logp | 3.300 |
No numbering system information yet
No physical and chemical property information yet
No safety information yet
No production method and use information yet
No upstream information yet
No downstream information yet
