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VTX-27

CAS number:1321924-70-2    molecular formula:C2OH24ClFN6O

overview

compound introduction

Information VTX-27 VTX-27 (Compound 27) is a potent and selective inhibitor of protein kinase C θ (PKC θ) with Ki of 0.08 nM and 16 nM for PKC θ and PKC δ, respectively. Targets PKCθ (Cell-free assay); PKCδ (Cell-free assay) 0.08 nM(Ki); 16 nM(Ki)

Specs

Chinese alias-
English alias2-​Piperazinemethanol,4-​[3-​chloro-​5-​fluoro-​6-​(1H-​pyrazolo[3,​4-​b]​pyridin-​3-​yl)​-​2-​pyridinyl]​-​α-​methyl-​α-​(1-​methylethyl)​-​,(αR,​2S)​-
CAS number1321924-70-2molecular formulaC2OH24ClFN6O
molecular weight418.9 g/molExact mass≥98%
PSA90.000 Ųlogp2.900

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