compound introduction
RKI-1447是一种有效的ROCK1和ROCK2抑制剂，IC50分别为14.5 nM和6.2 nM，有抗侵入和抗肿瘤活性。 RKI-1447 is a potent inhibitor of ROCK1 and ROCK2, with IC50 of 14.5 nM and 6.2 nM, respectively, has anti-invasive and antitumor activities.
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RKI-1447
CAS number：1342278-01-6 molecular formula：C16H14N4O2S
overview
Specs
| Chinese alias | - | ||
| English alias | NCGC00371153-09 | 1-[(3-hydroxyphenyl)methyl]-3-[4-(pyridin-4-yl)-1,3-thiazol-2-yl]urea | US9221808, 1bo-HCl | BR172011 | FD5032 | FT-0700170 | HY-15755 | compound 5g [PMID 23275831] | F8GZ6C9MKZ | Q27088558 | 1-(3-hydroxybenzyl)-3-(4-(pyridin-4-yl)thiazo | ||
| CAS number | 1342278-01-6 | molecular formula | C16H14N4O2S |
| molecular weight | 326.37 g/mol | Exact mass | - |
| PSA | 115.000 Ų | logp | 2.000 |
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