CAS number：1191951-57-1 molecular formula：C20H31N3O2S2
PHT-427是作用于Akt和PDPK1的双重抑制剂，Akt和PDPK1的PH结构域具有高度亲和力，Ki分别为2.7 μM和5.2 μM。A pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1). PHT-427 is a dual Akt and PDPK1 inhibitor (high affinity binding for the PH domains of Akt and PDPK1) with Ki of 2.7 μM and 5.2 μM, respectively A pleckstrin homology domain inhibitor to Akt and PKB Kinase (PDPK1).
| Chinese alias | - | ||
| English alias | J-515259 | PHT427 | PHT-427 | HB1251 | AS-69526 | AC-30264 | CCG-268762 | SB17376 | BP-30156 | BYWWNRBKPCPJMG-UHFFFAOYSA-N | J-004083 | HY-12063 | 4-Dodecyl-N-1,3,4-thiadiazol-2-ylbenzenesulfonamide | 4-Dodecyl-N-1,3,4-thiadiazol-2-yl-benzenesulfonamide | | ||
| CAS number | 1191951-57-1 | molecular formula | C20H31N3O2S2 |
| molecular weight | 409.61 g/mol | Exact mass | - |
| PSA | 109.000 Ų | logp | 7.400 |
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