CAS number：718630-59-2 molecular formula：C19H31N5O2
PHA-793887是一种新型有效的CDK2，CDK5和CDK7抑制剂，IC50分别为8 nM， 5 nM 和10 nM，作用于CDK2， 5，和7比作用于CDK1， 4，和9选择性高6倍以上。a novel pan-Cdk inhibitor inactive against 34 other kinases. PHA-793887 is a novel and potent inhibitor of CDK2, CDK5 and CDK7 with IC50 of 8 nM, 5 nM and 10 nM. It is greater than 6-fold more selective for CDK2, 5, and 7 than CDK1, 4, and 9. a novel pan-Cdk inhibitor inactive against 34 other kinases.
| Chinese alias | - | ||
| English alias | 3-Methyl-N-[1,4,5,6-tetrahydro-6,6-dimethyl-5-[(1-methyl-4-piperidinyl)carbonyl]pyrrolo[3,4-c]pyrazol-3-yl]butanamide | MLS006010173 | CCG-264898 | BCP02036 | SB19463 | AC-32848 | BDBM50378657 | C76289 | NCGC00263168-01 | NCGC00091316-02 | HMS3654B16 | MK | ||
| CAS number | 718630-59-2 | molecular formula | C19H31N5O2 |
| molecular weight | 361.48 g/mol | Exact mass | ≥95% |
| PSA | 81.300 Ų | logp | 1 |
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