PhiKan 083 hydrochloride 是一种咔唑衍生物,可以稳定 p53 的突变体 Y220C,Kd 值为 167 μM,在 Ln229 细胞中,相对亲和力 (Kd) 为 150 μM;PhiKan 083 可用于癌症研究。
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PhiKan083 hydrochloride
CAS number:1050480-30-2 molecular formula:C16H19ClN2
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| Chinese alias | 9-乙基-N-甲基-9H-咔唑-3-甲胺盐酸盐 | ||
| English alias | 9-Ethyl-N-methyl-9H-carbazole-3-methanamine hydrochloride | PK-083 hydrochloride | PhiKan-083 hydrochloride | PK083 hydrochloride | ||
| CAS number | 1050480-30-2 | molecular formula | C16H19ClN2 |
| molecular weight | 274.79 g/mol | Exact mass | ≥99%(HPLC) |
| PSA | 17.000 Ų | logp | - |
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