compound introduction
Atopaxar (E5555) 是一种高效、有口服活性活性的，选择性的，可逆的凝血酶受体蛋白酶激活受体-1 (PAR-1) 拮抗剂。Atopaxar 是一种抗血小板剂，能干扰血小板信号。Atopaxar 可用于动脉粥样硬化血栓性疾病的研究。 Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist. Atopaxar, an antiplatelet agent, interferes with platelet signaling. Atopaxar can be used for the research of atherothrombotic disease Information Atopaxar (E5555, ER-172594-00) is a potent and orally-active inhibitor of Protease-activated receptor-1 (PAR-1). E5555 inhibited the binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP) to PAR-1 with IC50 of 0.019μM.
