NSC319726是突变型p53R175再活化剂,能抑制表达p53R175的成纤维细胞增殖,IC50值为8nM,对野生型p53细胞无抑制作用。 NSC319726 is a p53(R175) mutant reactivator, exhibits growth inhibition in cells expressing mutant p53, with IC50 of 8 nM for p53(R175) mutant, shows no inhibition for p53 wild-type cells.
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NSC 319726
CAS number:71555-25-4 molecular formula:C11H14N4S
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| Chinese alias | - | ||
| English alias | NSC 319726 | s7149 | BRD-K99170882-001-01-9 | A899911 | Azetidinecarbothioic acid, [1-(2-pyridinyl)ethylidene] hydrazide | CCG-35689 | AKOS024458479 | N'-(1-(Pyridin-2-yl)ethylidene)azetidine-1-carbothiohydrazide | EX-A2113 | LS-13960 | N-[(E)-1-pyridin-2 | ||
| CAS number | 71555-25-4 | molecular formula | C11H14N4S |
| molecular weight | 234.32 g/mol | Exact mass | ≥95% |
| PSA | 72.600 Ų | logp | 1.400 |
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