CAS number：1601496-05-2 molecular formula：C19H15N5S2
描述： GSK-843 (GSK'843) 是一种受体相互作用蛋白激酶 3 (RIP3 or RIPK3) 抑制剂，高亲和力结合 RIP3 激酶结构域，IC 50 值为 8.6 nM，并抑制激酶活性 IC 50 值为 6.5 nM。GSK-843 可用于炎症的研究。 GSK-843 (GSK'843) is a receptor-interacting protein kinase 3 (RIP3 or RIPK3) inhibitor, which has a high affinity for binding to the RIP3 kinase domain with an IC50 value of 8.6 nM and an IC50 value of 6.5 nM for inhibiting kinase activity. GSK-843 can be used in the study of inflammation.
| Chinese alias | 3-(5-苯并噻唑基)-7-(1,3-二甲基-1H-吡唑基-5-基)-噻吩并[3,2-c]吡啶-4-胺 | ||
| English alias | 3-(5-Benzothiazolyl)-7-(1,3-dimethyl-1H-pyrazol-5-yl)-thieno[3,2-c]pyridin-4-amine | GSK 843 | GSK843 | GSK′843 | ||
| CAS number | 1601496-05-2 | molecular formula | C19H15N5S2 |
| molecular weight | 377.48 g/mol | Exact mass | - |
| PSA | 126.000 Ų | logp | 4.000 |
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