Poly (I:C):Kanamycin (1:1) sodium is an isometric complex of Poly (I:C) ( HY-135748 ) and Kanamycin ( HY-16566 ). Poly(I:C) sodium, a synthetic analog of double-stranded RNA, is a TLR3 and retinoic acid-inducible gene I receptor ( RIG-I and b>MDA5 ) agoni Appearance:Solid IC50& Target:TLR3 , RIG-I , MDA5 , apoptosis In Vitro:Poly (I:C) sodium (20 ng/mL; 24 hours; WM793, WM278, WM239A, WM9 and 1205Lu cells) treatment strongly reduces viability from 100% in controls to 20%–50% within 24 hours. Poly (I:C) sodium (200 ng/mL; 24 hours; 1205Lu cells) treatment induces apoptosi In Vivo:Poly (I:C) sodium treatment inhibits tumor growth in NOD/SCID immunodeficient mice injected with 1205Lu cells. The level of human DNA is 50% lower in mice treated with Poly (I:C) sodium. Kanamycin (2, 4mg/kg; s.c.; once daily, 6 times a week for 3 w Biological Activity:Poly (I:C):Kanamycin (1:1) sodium is an isometric complex of Poly (I:C) ( HY-135748 ) and Kanamycin ( HY-16566 ). Poly(I:C) sodium, a synthetic analog of double-stranded RNA, is a TLR3 and retinoic acid-inducible gene I receptor ( RIG-I and b>MDA5 ) agoni
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Poly (I:C):Kanamycin (1:1) (sodium)
CAS number：unknown molecular formula：
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| Chinese alias | 聚(I:C)：卡那霉素(1:1)(钠) | ||
| English alias | - | ||
| CAS number | unknown | molecular formula | |
| molecular weight | - | Exact mass | - |
| PSA | - | logp | - |
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