5-NIdR (1-(β-D-2-Deoxyribofuranosyl)-5-nitroindole) 是一种人工核苷,具有抑制Temozolomide 产生的 DNA 损伤复制的能力。5-NIdR 诱导癌细胞凋亡 (apoptosis) 并使细胞周期停滞在 G0 期。5-NIdR 增强替莫唑胺在小鼠胶质母细胞瘤模型中的抗肿瘤功效。
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1-(2-Deoxy-b-D-ribofuranosyl)-5-nitroindole
CAS number:191421-10-0 molecular formula:
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| Chinese alias | - | ||
| English alias | - | ||
| CAS number | 191421-10-0 | molecular formula | |
| molecular weight | 278.260 g/mol | Exact mass | ≥98% |
| PSA | 100.000 Ų | logp | 1.200 |
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