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N-(4-chlorophenyl)-5-nitrofuran-2-carboxamide

CAS number:109844-92-0    molecular formula:C11H7ClN2O4

overview

compound introduction

LCS3 是可逆性和非竞争性的谷胱甘肽二硫化物还原酶 (GSR) 和硫氧还蛋白还原酶1 (TXNRD1) 抑制剂 (IC50分别为 3.3 µM 和 3.8 µM)。LCS3 表现出抗肿瘤活性,并诱导细胞凋亡,可用于肺腺癌 (LUAD) 的研究。

Specs

Chinese alias-
English alias-
CAS number109844-92-0molecular formulaC11H7ClN2O4
molecular weight266.64 g/molExact mass≥98%
PSA88.100 Ųlogp2.900

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